Our research involves biomechanical instrumentation for measuring and modelling human biodynamics in daily conditions, during spontaneous activity or physical exercises.Based on body worn sensors, we design wearable systems and algorithms for long-term monitoring of physical activity and gait analysis, for the estimation of the 3D joint kinematics and kinetics, and for the sport performance evaluation. This involves advanced signal processing, multi-parametric approach, sensors’fusion and functional calibration methods to devise new methods for activity recognition and to extract relevant disease/health related features hidden in human biomechanical signals.